tl;dr: Data from thousands of non-retracted articles indicate that experiments published in higher-ranking journals are less reliable than those reported in ‘lesser’ journals. Vox health reporter Julia Belluz has recently covered the reliability of peer-review.

This is a slightly edited (amended, essentially) version of my article published today at The Conversation. In cases where a problem within a community is detected and collective action is required to address the problem. one needs to strike a fine line or any efforts to convince the community that action is required will fail.