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Science in the Open

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I had a pretty ropey day today. Failing for 45 minutes to do some simple algebra. Transformation overnight that didn’t work…again…and just generally being a bit down what with the whole imploding British science funding situation. But in the midst of this we did one very cool and simple experiment, one that worked, and one that actually has some potentially significant implications. The only things is…I can’t tell you about it.

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The rationale behind open approaches is the way it enables you to make unexpected connections and to find otherwise hidden shortcuts. People, data, code, and expertise can be more effectively connected when the information is out there and discoverable. Here I wanted to document a little collaboration that was sparked on twitter and carried through using an entirely open toolset.

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Issues surrounding the relationship of Open Research and replication seems to be the meme of the week. Abhishek Tiwari provided notes on a debate describing concerns about how open research could damage replication and Sabine Hossenfelder explored the same issue in a blog post.

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On Monday 1 September we had a one day workshop in Southampton discussing the issues that surround ‘Open Science’. This was very free form and informal and I had the explicit aim of getting a range of people with different perspectives into the room to discuss a wide range of issues, including tool development, the social and career structure issues, as well as ideas about standards and finally, what concrete actions could actually be taken.

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So a bit of a first for me. I can vaguely claim to have contributed to two things into the print version of Nature this week. Strictly speaking my involvement in the first, the ‘From the Blogosphere‘ piece on the Science Blogging Challenge, was really restricted to discussing the idea (originally from Richard Grant I believe) and now a bit of cheerleading and ultimately some judging.

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So Michael Nielsen, one morning at breakfast at Scifoo asked one of those questions which never has a short answer; ‘So how did you get into this open science thing?’ and I realised that although I have told the story to many people I haven’t ever written it down.

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A story of two major retractions from a well known research group has been getting a lot of play over the last few days with a News Feature (1) and Editorial (2) in the 15 May edition of Nature. The story turns on claim that Homme Hellinga’s group was able to convert the E. coli ribose binding protein into a Triose phosphate isomerase (TIM) using a computational design strategy.