The Yale University science libraries have decided to cancel their Biomed Central membership. Dramatically increasing page charges are the reason behind this decision. Other former members of Biomed Central include the Centers for Disease Control and Prevention (CDC), Brown University, The Jackson Laboratory, the drug company Eli Lilly, University of Oxford, Cancer Research UK, EMBL and DKFZ in Heidelberg, and many others.

The National Institutes of Health (NIH) is currently recommending public access of all papers from NIH-funded research. Fewer than 5% of research papers have gone this route since the policy went into effect in 2005. On July 19, 2007 the House of Representatives passed the FY2008 Labor, HHS, and Education Appropriations Bill that will make public access within 12 months of publication a requirement for all NIH-funded work.