(Please note that this post was updated on 12th Dec 2020 – see below) This week DeepMind has announced that, using artificial intelligence (AI), it has solved the 50-year old problem of ‘protein folding’. The announcement was made as the results were released from the 14 ^th and latest competition on the Critical Assessment of Techniques for Protein Structure Prediction (CASP14). The competition pits teams of computational

At the risk of getting uber-meta, here is a blog post about writing my latest blog post at the Guardian. This was an account of a scientific discovery, albeit a minor one, that occurred during the process of shepherding the latest paper from my lab to publication. Why write about writing this post? Because maybe it will help others, and maybe it will help me to think it through.

I got impatient waiting for my latest review article to come out, so here it is. The scheduled publication date has slipped twice now without the publisher getting in touch to explain why. The latest I’ve heard, after querying the editor who commissioned the piece, is that it will be out by the end of the month. But I’ve paid my £500 fee to make the work open access and don’t see any good reason to delay further.

It’s funny how one thing leads to another. The video of my Friday Evening Discourse at the Royal Institution last year caught the attention of a former colleague and produced an invitation to contribute a lecture to her plans to celebrate the International Year of Crystallography at the University of Western Australia in Perth this summer.

The Royal Institution has made a rather lovely film about William and Lawrence Bragg, the father and son Nobel laureates who came up the method of structural analysis by X-ray crystallography around 100 years ago. The film is constructed around an interview with Lawrence Bragg’s daughter Patience, a delightful lady who has very fond memories of her father and some wonderful stories about him.

I may not know much about Chemistry but I know what I like. And I like carbon. In fact, I’ve decided that it’s my favourite element. I’ll tell you why in the short video below, which is part of the Royal Institution’s 2012 Advent Calendar.     Please take a little time to explore the rest of the calendar.

What’s your favourite colour? Anyone who has socialised with small children will have been confronted with this serious-faced interrogation at some point. It’s the sort of question that erupts as soon as young kids learn to verbalise the jumble of perceptions filling up minds that are untidier than bedrooms. It’s the sort of question that is too often discarded in the mis-named process of growing up. So what do you answer? Blue? Green?

Regular readers will know that molecules are my thing, that my scientific endeavours are devoted to revealing the intricate architecture of proteins — the molecular machines that sustain life. They will also know that I have at times struggled with the problem of how to write about molecules in a way that might grab the attention of those who rarely think about them.

On a grey day back in October I made my way along Albemarle Street to the Royal Institution for the filming of DemoJam, a lively and light-hearted program of science produced by Jonathan Sanderson and the rest of the gang at StoryCog for the new RI channel.

Last week I went to Germany to talk to a pharmaceutical company about my work on the blood protein, human serum albumin. It set me thinking. But first I need to tell you about albumin. Albumin is a surprisingly abundant protein in the human body;