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Quintessence of Dust

Quintessence of Dust explores science, society, and human nature, focusing on genetics, development, evolution, neuroscience, systems biology, and topics related to scientific literacy. I occasionally discuss intelligent design, creationism, science denial, and other political/social influences on scientific literacy. Additional topics: philosophy, baseball, scientific culture, and Shakespeare. My main theme is scientific explanation.
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Author Stephen Matheson

I do apologize for this dull cliche, but I know I'm right about this: change is hard. I don't mean that it's hard to adapt after someone or something forces a change on you. That's true too, but it's not my topic here. I'm talking about this: you want to change, or you need to change, or both. You know what the change has to be. Maybe you know what the first step has to be. It's change, and it's hard.

Published
Author Stephen Matheson

The concept of randomness is caught up in evolution, in two broad ways. The first and most famous aspect is the oft-misunderstood randomness of mutation. The second aspect is the role of chance in the trajectory of evolution. It is this question—is evolution predictable, or is it a random "drunkard's walk"—that Conway Morris tackles in the second chapter of From Extraterrestrials to Animal Minds: Six Myths of Evolution.

Published
Author Stephen Matheson

Warning: this post includes spoilers for Black Widow , Avengers: Endgame , and Spider-Man: No Way Home . Seems a small price to pay to understand the biophysical limits of the biosphere, but it's your call. So, are you sure you want that superpower? Have you noticed that superheroes usually have difficult lives and crushing responsibilities?

Published
Author Stephen Matheson

It was the subtitle of this book ( From Extraterrestrials to Animal Minds: Six Myths of Evolution by Simon Conway Morris) that reeled me in, combined with my inability to resist reading the thoughts of Conway Morris on what that subtitle advertises: "Six Myths of Evolution." I'm about halfway through the book, and through three of the six myths.

Published
Author Stephen Matheson

A few months ago, we were looking at the concept of a fitness landscape and how new technologies are creating opportunities for biologists to look in detail at relationships between genetics and fitness. The first post discussed the concepts of a fitness landscapes and adaptive walks, with some focus on the limitations of the metaphor.

Published
Author Stephen Matheson

A couple of months ago we started looking at the concept of fitness landscapes and at some new papers that have significantly expanded our knowledge of the maps of these hypothetical spaces. Recall that a fitness landscape, basically speaking, is a representation of the relative fitness of a biological entity, mapped with respect to some measure of genetic change or diversity.

Published
Author Stephen Matheson

Thinking about fitness landscapes can stimulate detailed discussion and consideration of the meanings and limitations of such metaphors, and my introductory comments at The Panda's Thumb did just that. Most notably, Joe Felsenstein pointed us to the various ways these depictions can be employed, and urged everyone to use caution in interpreting them.