Google has a new experimental1 tool called Illuminate ( illuminate.google.com ) that takes a link to a preprint2 and creates a podcast discussing the paper. When I tested this with a few preprints, the podcasts it generated are about 6-8 minutes long, featuring a male and female voice discussing the key points of the paper in a conversational style. There are some obvious shortcomings.

This week’s recap highlights a new tool from Wei Shen and Zamin Iqbal for efficient sequence alignment against millions of prokaryotic genomes (LexicMap), a new tool from Heng Li for efficiently constructing and querying a sequence index at scale, an R/Bioconductor package for detecting and correcting DNA contamination in RNA-seq data, a method for dating gene age using synteny, how AlphaFold predictions for some types of conformations are

This is an experiment... ignore this post

This week’s recap highlights Google/Deepmind’s new AlphaProteo tool for protein design, tools for protein structure alignment and analysis, biases in polygenic risk scores due to overlap and kinship, highly variable gene selection in single cell RNA-seq, and reconstruction of a 4.2 billion year old last universal common ancestor of life on Earth (spoiler alert: CRISPR-Cas is >4B years old!). Others that caught my attention include a new

This week’s recap highlights perspectives in de-extinction and patent law, systematic benchmarking of scATAC-seq methods, a 91 gigabase (!) animal genome, structural variant genotyping with long reads, cell type-specific enhancer prediction, and a perspective piece in AI in biosecurity.

Here are a few papers that caught my attention recently. I summarize a few in the deep dive at the top, then link to a few other papers of note later on. Subscribe to Paired Ends to get periodic summaries like this delivered to your e-mail.

Here are a few papers that caught my attention recently. I summarize a few in the deep dive at the top, then link to a few other papers of note later on. Subscribe to Paired Ends to get periodic summaries like this delivered to your e-mail.

Here are a few papers that caught my attention recently. I summarize a few in the deep dive at the top, then link to a few other papers of note later on. Subscribe to Paired Ends to get periodic summaries like this delivered to your e-mail.

It’s been a big week in the genomics+bioinformatics space. This post expands on a few of the recent papers I posted in a Twitter thread. I highlight a few in the deep dive at the top, then link to a few other papers of note later on. Subscribe (free!) to Paired Ends to get summaries like this delivered to your e-mail as soon as I write them.

This post expands on a few of the papers I posted in this Twitter thread. I highlight a few in the deep dive at the top, then link to a few other papers of note later on. Subscribe to Paired Ends to get summaries like this delivered to your e-mail as soon as I write them. Subscribe now You might remember me from Getting Genetics Done where I blogged about genetics, statistics, and bioinformatics from 2008-2017.