Interesting ChemistryReaction MechanismAccessible Activation Free EnergyAryneAzulenesChemical Sciences
Published in Henry Rzepa's Blog
Author Henry Rzepa
The story so far. Inspired by the report of the most polar neutral compound yet made, I suggested some candidates based on the azulene ring system that if made might be even more polar. This then led to considering a smaller π-analogue of azulene, m-benzyne. Here I ponder how a derivative of this molecule might be made, using computational profiling as one reality check.