This week in GigaScience , Hasindu Gamaarachchi and colleagues published a paper on their HARU solution for selective sequencing, to be used alongside the handheld (“tricorder” like) Nanopore MinION device . With the MinION, it is possible to kick out all non-target DNA strands before they are processed through the device’s pores, thus selectively sequencing specific target regions of the genome.