Interesting ChemistryReaction MechanismAnaestheticDiazirineGABAA ReceptorsChemical SciencesIsoelectronic games: the CO analogue of diazirines as an intriguing species?https://doi.org/10.59350/9b8by-g0221Published September 24, 2015 in Henry Rzepa's BlogAuthor Henry RzepaExportCitationHow does an anaesthetic work?
Organic ChemistryClinical BiochemistryDrug DiscoveryPharmaceutical ScienceMolecular BiologyDiazirine based photoaffinity labelinghttps://doi.org/10.1016/j.bmc.2011.06.066Published January 1, 2012 in Bioorganic & Medicinal ChemistryAuthors Luba Dubinsky, Bastiaan P. Krom, Michael M. Meijler
Cell BiologyMolecular BiologyA propofol binding site on mammalian GABAA receptors identified by photolabelinghttps://doi.org/10.1038/nchembio.1340Published September 22, 2013 in Nature Chemical BiologyAuthors Grace M S Yip, Zi-Wei Chen, Christopher J Edge, Edward H Smith, Robert Dickinson, Erhard Hohenester, R Reid Townsend, Karoline Fuchs, Werner Sieghart, Alex S Evers, Nicholas P Franks
Drug DiscoveryPharmacologyGeneral MedicineThe therapeutic potential of carbon monoxidehttps://doi.org/10.1038/nrd3228Published September 1, 2010 in Nature Reviews Drug DiscoveryAuthors Roberto Motterlini, Leo E. Otterbein
InChI=1/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2/t2-/m1/s1AQZRARFZZMGLHL-UWTATZPHSA-NC3HF3Ohttps://doi.org/10.14469/ch/191532Published September 24, 2015Authors Henry S Rzepa, Imperial College London, Imperial College London, Henry S Rzepablog