Interesting ChemistryAcidAcidsBicyclic NetworkCarboxylic AcidChemical Sciences

I’ve started so I’ll finish. Kinetic isotope effect models for a general acid as a catalyst in the protiodecarboxylation of indoles.

https://doi.org/10.59350/fvk36-yzf26
Published in Henry Rzepa's Blog

Earlier I explored models for the heteroaromatic electrophilic protiodecarboxylation of an 3-substituted indole, focusing on the role of water as the proton transfer and delivery agent. Next, came models for both water and the general base catalysed ionization of indolinones.

References

InChI=1S/C9H7NO2.ClH.4H2O/c11-9(12)7-5-10-8-4-2-1-3-6(7)8;;;;;/h1-5,10H,(H,11,12);1H;4*1H2WMAPUJHIXRYTID-UHFFFAOYSA-N

C9H16ClNO6

https://doi.org/10.14469/ch/191767
Published
Authors Henry S Rzepa, Imperial College London, Imperial College London, Henry S Rzepa

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