Published in Henry Rzepa's Blog
Author Henry Rzepa
In this series of posts on optical rotations, I firstly noted Kirkwood’s 1937 attempt to correlate the optical rotation of butan-2-ol with its absolute configuration.
In this series of posts on optical rotations, I firstly noted Kirkwood’s 1937 attempt to correlate the optical rotation of butan-2-ol with its absolute configuration.
In dilute aqueous solutions, D-glyceraldehyde exists both in the free and hydrated monomeric forms; the equilibrium between them depends on the temperature. The specific rotation of the equilibrium mixture was measured polarimetrically in the temperature range from 20 to 80 °C, the concentrations of both forms being determined by 1H NMR spectroscopy. From these data, the specific rotations of both forms of D-glyceraldehyde in the indicated temperature range were calculated.