Reaction MechanismAl-H-Li BridgeDihydrocinnamyl Alcohol Reduction ProductFree EnergyImperial CollegeChemical Sciences
Published in Henry Rzepa's Blog
Author Henry Rzepa
The reduction of cinnamaldehyde by lithium aluminium hydride (LAH) was reported in a classic series of experiments[cite]10.1021/ja01197a060[/cite],[cite]10.1021/ja01202a082[/cite],[cite]10.1021/ja01190a082[/cite] dating from 1947-8. The reaction was first introduced into the organic chemistry laboratories here at Imperial College decades ago, vanished for a short period, and has recently been reintroduced again. ‡ The experiment is